Accelerate your single-cell cloning work with the isoCell

Single-cell cloning at the microscale

The isoCell introduces a completely new approach to single-cell cloning by harnessing the power and benefits of microscale fluid-shaping. The isoCell provides high-level automation where it matters, enforces a highly convenient and consistent workflow, and requires almost no training.
It has an incredible small footprint and little weight, making it very portable with almost no space requirement — ideal for any laminar flow hood.
As a multi-user instrument the isoCell stores data and handles several experiments from multiple users simultaneously with ease.

Meet the isoCell — Winner of the SLAS2018 'New Product Award'!

isoCell front view

The only '3-in-1' solution for single-cell cloning

  • Automated cell plating
  • Automated feeding
  • Automated harvesting
isoCell front view turned to the left

Crystal-clear visibility of single cells on any microscope

  • Free of optical edge-effects
  • Instant visibility of cells right after plating
  • Assurance of monoclonality
isoCell side view jetting system

Stop wasting precious samples and reagents

  • Accurate nanoliter pipetting
  • Working volumes below 1 μl
  • Massive savings of precious material

isoCell — automate your single-cell cloning workflow

Create a GRID on 60-mm round-bottom dishes, comprising 256 individual chambers (equiv. to 2½ 96-well plates)

60-mm polystyrene dish

Automated dispensing of cells into GRID chambers (visualised here by dyed cell-culture medium)

60-mm polystyrene dish with GRID

Automated feeding of GRID chambers that contain single cells (specified by user via convenient GRID coordinates)

60-mm polystyrene dish with GRID and extra cell culture medium

Automated retrieval of colonies for downstream workflows

60-mm polystyrene dish with GRID and cell culture medium removed

Sideview of a GRID; three chambers were selectively filled with varying amounts of dyed cell-culture medium (orange)

Sideview of a GRID

Phase-contrast image of six chambers of a GRID. Image was taken after filling the chambers with cell-culture medium

Phase-contrast microscope image of GRID

  • Unparalleled optical clarity

  • Massive savings of reagents

  • Compatible with stem-cell coatings

Request a demo

Get in touch if you want to learn more about the isoCell and/or request a demo