Freestyle Fluidics breaks the rules of traditional microfluidics by radically simplifying the making, operation and integration of microfluidic devices. It is ideally suited to explore cells under precisely controllable, customisable and dynamic flow regimes at the microscale. Liquid microfluidic circuits are extremely stable and can be operated with passive- or active pumping mechanisms.
Microfluidic circuits made with Freestyle Fluidics are held in place via interfacial tension. Circuits are made much the same way as drawing a pattern on a piece of paper with a pen. After the aqueous liquid pattern has been created, a second immiscible liquid is overlaid. Hence, circuits are now bonded via liquid walls (and not solid ones).
"We study bacterial biofilms and how cells behave in flow and chemical gradients. The great advantage of the iota system for us is the potential to have, after a microfluidic experiment, direct access to the cells for follow up studies. Conventional walled microfluidic systems are closed and sealed making it very hard to get the cells out after studying them. With iota, therefore, we can develop more powerful protocols to study cells that have been in, and then outside, of the device."